Hub metastatic gene signature and risk score of breast cancer patients with small tumor sizes using WGCNA.

Yu-Tien ChangZhi-Jie HongHsueh-Han TsaiAn-Chieh FengTzu-Ya HuangJyh-Cherng YuKuo-Feng HsuChi-Cheng HuangWei-Zhi LinChi-Ming ChuChia-Ming LiangGuo-Shiou Liao

Published in: Breast cancer (Tokyo, Japan) (2024)

Prognostic gene signature was predictive of DMFS for BCs with small tumor sizes. The protein-protein interaction network of PIK3R1, IL1R1, MMP11, GOLM1, and VAV3 connected by EGFR merits further experiments for elucidating the underlying mechanisms.

Keyphrases

protein protein
small cell lung cancer
small molecule
copy number
genome wide
squamous cell carcinoma
epidermal growth factor receptor
tyrosine kinase
gene expression
young adults
bioinformatics analysis