P. gingivalis in oral-prostate axis exacerbates benign prostatic hyperplasia via IL-6/IL-6R pathway.

Shuang-Ying WangYi CaiXiao HuFei LiXin-Hang QianLing-Yun XiaBo GaoLan WuWen-Zhong XieJia-Min GuTong DengCong ZhuHai-Chang JiaWan-Qi PengJiao HuangCheng FangXian-Tao Zeng

Published in: Military Medical Research (2024)

P. gingivalis was abundant in the Pf of patients with BPH concurrent periodontitis. P. gingivalis infection can promote BPH, which may affect the progression of BPH via inflammation and the Akt signaling pathway.

Keyphrases

benign prostatic hyperplasia
lower urinary tract symptoms
signaling pathway
oxidative stress
pi k akt
epithelial mesenchymal transition
induced apoptosis
prostate cancer