Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations.
Alexandra G MillsAmy C DupperKieran I ChackoBremy AlburquerqueDevika NadkarniAna Berbel CabanLindsey FoxMelissa Randy GitmanAjay OblaHarm van BakelDeena R AltmanPublished in: Antimicrobial stewardship & healthcare epidemiology : ASHE (2023)
This case-control study of 25 cases with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia with vancomycin minimum inhibitory concentration (MIC) ≥ 2 µg/mL and 391 controls (MIC < 2 µg/mL) characterized the clinical characteristics, treatments, and outcomes associated with elevated vancomycin MIC. Elevated vancomycin MIC was associated with baseline hemodialysis, prior MRSA colonization, and metastatic infection.