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ZBP1 promotes hepatocyte pyroptosis in acute liver injury by regulating the PGAM5/ROS pathway.
Shengguang Yan
Lina Yu
Ziren Chen
Dan Xie
Zuli Huang
Shi Ouyang
Published in:
Annals of hepatology (2024)
ZBP1 promotes hepatocellular pyroptosis by modulating mitochondrial damage, which facilitates the extracellular release of ROS.
Keyphrases
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liver injury
drug induced
oxidative stress
dna damage
cell death
nlrp inflammasome
reactive oxygen species
signaling pathway
liver failure
respiratory failure
intensive care unit
hepatitis b virus
acute respiratory distress syndrome