A phase II study of S-1 therapy for patients with advanced and recurrent esophageal cancer resistant or intolerable to fluorouracil, platinum, and taxane therapy (OGSG 1404).
Motoo NomuraTakayuki KiiJunji KawadaMasashi HirotaTakashi OhtaJin MatsuyamaDaisuke SakaiToshio ShimokawaYukinori KurokawaHisato KawakamiToshimasa TsujinakaTaroh SatohPublished in: Esophagus : official journal of the Japan Esophageal Society (2022)
Although this trial closed early because of slow accrual, we observed modest clinical activity with S-1 in patients with R/M ESCC who could not tolerate or whose tumors were refractory to FU, PT, and TAX therapy.