SV40 Large T Antigen Disrupts Embryogenesis of Canine and Porcine Somatic Cell Nuclear Transfer Embryo.

Kiyoung EunSeon-Ung HwangYeon Woo JeongSunyoung SeoSeon Yong LeeWoo Suk HwangSang-Hwan HyunHyunggee Kim

Published in: Biological procedures online (2017)

Although lifespan-extended canine and porcine cells via SV40LT exhibit no apparent transforming changes, they are inappropriate for use as nuclei donors for SCNT because of their aneuploidy.

Keyphrases

induced apoptosis
cell cycle arrest
single cell
cell therapy
oxidative stress
cell death
diffusion weighted imaging
gene expression
pregnant women
computed tomography
magnetic resonance
pregnancy outcomes
transcription factor
cell proliferation
genome wide
electron transfer