Blastic plasmacytoid dendritic cell neoplasm.

Manoj Ponadka RaiPrabhjot Singh BediSamanjit Kaur KandolaShilpa KavuturuRashi Singhal

Published in: Clinical case reports (2018)

Blastic plasmacytoid dendritic cell neoplasm is an aggressive neoplasm with a median survival of only a few months despite treatment. An exhaustive immunohistochemical workup is required to differentiate it from myeloid sarcoma and extranodal NK/T cell lymphoma. Treatment is with induction using a regimen utilized for leukemia. Allogeneic hematopoietic stem cell transplantation is recommended for those who achieve remission following induction.

Keyphrases

dendritic cells
regulatory t cells
immune response
allogeneic hematopoietic stem cell transplantation
acute myeloid leukemia
low grade
acute lymphoblastic leukemia
bone marrow
combination therapy
high grade
disease activity
replacement therapy