Insulin Secretion, Sensitivity, and Kidney Function in Young Individuals With Type 2 Diabetes.
Petter BjornstadYe Ji ChoiCarson PlatnickSusan GrossPhoom NarongkiatikhunIsabella MelenaLauryn RemmersMadison BacaGrant SchutteTyler DobbsTim VigersLaura PyleLynette DriscollKalie TommerdahlJessica KendrickHelen C LookerAllison DartDavid CherneyDaniel H van RaalteAnand SrivastavaLuping LiPottumarthi PrasadPierre SaulnierRobert G NelsonRichard J JohnsonKristen J Nadeaunull nullPublished in: Diabetes care (2023)
Youth with type 2 diabetes demonstrated severe β-cell dysfunction that was associated with intraglomerular hypertension and kidney hyperoxia. Similar but attenuated findings were found in OCs.