Neuroprotective effect of epigallocatechin-3-gallate (EGCG) on radiation-induced damage and apoptosis in the rat hippocampus.

Mohamed Amr El-Missiry Ibrahim M El-SherbinyMamdouh R El-SawyMohamad F Lebede

Published in: International journal of radiation biology (2018)

EGCG can attenuate the severity of radiation-induced damage and cell death in hippocampus recommending polyphenols as successful option for protecting against radiation-induced hippocampal damage.

Keyphrases

radiation induced
oxidative stress
cell death
cerebral ischemia
radiation therapy
cell cycle arrest
endoplasmic reticulum stress
cognitive impairment
blood brain barrier
prefrontal cortex
brain injury
temporal lobe epilepsy