Prognostic Implications of MALAT1 and BACH1 Expression and Their Correlation with CTCs and Mo-MDSCs in Triple Negative Breast Cancer and Surgical Management Options.

Samah Said ElbasateenyMahmoud Abdou YassinMohamed Mahmoud MokhtarAdel Mohamed IsmailHuda Fathy EbianSamia HusseinSherin Attia ShazlyMai Mohammed Abdelwabab

Published in: International journal of breast cancer (2022)

BACH1 and MALAT1 expressions are significantly upregulated in TNBC. They are correlated with CTCs and Mo-MDCs, and all are associated with poor outcomes. Not all TNBC patients have a bad prognosis, patients negative for one of MALAT1 and BACH1 or both, have a slightly good prognosis, and so can be managed by breast oncoplastic conserving surgery.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
circulating tumor cells
minimally invasive
squamous cell carcinoma
skeletal muscle
lymph node
radiation therapy
acute coronary syndrome
percutaneous coronary intervention
insulin resistance
locally advanced
surgical site infection