Neonatal hemophagocytic lymphohistiocytosis: A meta-analysis of 205 cases.

Lincoln A KranzWyatt S HahnWhitney S ThompsonRoland HentzNathan L KobrinskyPaul J Galardy Jacob R Greenmyer

Published in: Pediatric blood & cancer (2024)

Evaluation of nHLH requires rapid testing for a wide range of differential diagnoses. HLH diagnostic criteria such as fever and bicytopenia may not occur as frequently in the neonatal population as in older pediatric populations. Neurologic and hepatic manifestations frequently occur in the neonatal population. Current reports of nHLH suggest a high mortality rate. Future publications containing data on nHLH should improve reporting quality by reporting all clinically relevant data.

Keyphrases

adverse drug
electronic health record
big data
physical activity
risk factors
cardiovascular disease
type diabetes
data analysis
community dwelling
loop mediated isothermal amplification