Comprehensive Treatment and Gene Analysis of a Male Patient with Follicular Occlusion Tetrad with Fordyce Granules.

Published in: Clinical, cosmetic and investigational dermatology (2024)

Follicular occlusion tetrad (FOT) is a chronic inflammatory skin disease that seriously affects patients' quality of life. At present, there is no standard treatment plan for FOT. We report the case of a 50-year-old male patient diagnosed as having FOT with Fordyce granules and type 2 diabetes mellitus. During hospitalization, the patient received comprehensive and systematic treatment. The patient healed well after surgery and the 10-month follow-up revealed no recurrence. We found eight gene mutations by whole-exome sequencing (WES) of the patient's peripheral blood.

Keyphrases

case report
peripheral blood
end stage renal disease
chronic kidney disease
cardiovascular disease
combination therapy
gene expression
metabolic syndrome
prognostic factors
adipose tissue
transcription factor
peritoneal dialysis
copy number
genome wide identification