Early-life adversity severity, timing, and context type are associated with SLC6A4 methylation in emerging adults: Results from a prospective cohort study.
Stephanie M KoningCourtenay L KesslerTurhan CanliElif A DumanEmma K AdamRichard ZinbargMichelle G CraskeJacquelyn E StephensSuzanne Vrshek-SchallhornPublished in: Psychoneuroendocrinology (2024)
Results further implicate epigenetic modification on serotonergic neurotransmission via DNAm in the downstream sequelae of ELA-particularly adolescent deprivation-and support preventive interventions in adolescence to mitigate biological embedding.