Buyang Huanwu Decoction suppresses ischemic stroke by suppressing glycolysis and cell apoptosis in rat brain microvascular endothelial cells.

Ci SongXia FangNi FangFang Hu

Published in: Brain research bulletin (2024)

In summary, BHD inhibited glycolysis and apoptosis via suppressing the pan-kla and H3K18la protein levels and the Apaf-1 transcriptional activity, thus restraining the progression of IS.

Keyphrases

endothelial cells
signaling pathway
oxidative stress
endoplasmic reticulum stress
cell cycle arrest
gene expression
cell proliferation
atrial fibrillation
transcription factor
cell death
pi k akt
protein protein
amino acid
binding protein
vascular endothelial growth factor
heat shock
small molecule
heat stress