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Entire Mitral Valve Reconstruction Using Porcine Extracellular Matrix: Adding a Ring Annuloplasty.

Johannes H JedrzejczykStine KrogSøren Nielsen SkovKaren B PoulsenMona SharghbinLeila Louise BenhassenSten L NielsenJohn Michael HasenkamMarcell J Tjørnild
Published in: Cardiovascular engineering and technology (2024)
We successfully reconstructed the entire mitral valve using 2-ply small intestinal submucosal extracellular matrix (CorMatrix®) combined with a flexible annuloplasty. The annuloplasty reduced the unphysiological systolic widening previously found with this reconstructive technique. However, the Simulus flex ring changed the physiological annular D-shape into a circular shape and hindered a correct unfolding of the leaflets. Thus, we do not recommend a flexible ring in conjunction with this reconstructive technique; further investigations are needed to discover a more suitable remodelling annuloplasty.
Keyphrases
  • mitral valve
  • extracellular matrix
  • left ventricular
  • left atrial
  • heart failure
  • blood pressure
  • atrial fibrillation
  • solid state