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Increased serum PCSK9, a potential biomarker to screen for periodontitis, and decreased total bilirubin associated with probing depth in a Japanese community survey.

Koichi TabetaM HosojimaM NakajimaS MiyauchiH MiyazawaN TakahashiY MatsudaN SugitaY KomatsuK SatoT IshikawaK AkiishiKazuhisa YamazakiK KatoA SaitoH Yoshie
Published in: Journal of periodontal research (2018)
In Japanese male subjects, the concentrations of serum PCSK9 and TBIL were correlated with periodontal parameters. Moreover, PCSK9 could be a candidate biomarker for diagnosing chronic periodontitis, and may also have potential to evaluate the risk for periodontitis to cause ASVD. Longitudinal studies of larger populations are necessary to confirm the exact association of periodontitis with increased serum PCSK9 and decreased TBIL.
Keyphrases
  • low density lipoprotein
  • healthcare
  • mental health
  • high throughput
  • optical coherence tomography
  • single molecule
  • human health