Mitochondrial measures in neuronally enriched extracellular vesicles predict brain and retinal atrophy in multiple sclerosis.
Dimitrios C LadakisPamela J YaoMichael VreonesJoseph BlommerGrigorios KalaitzidisElias S SotirchosKathryn C FitzgeraldShiv SaidhaPeter A CalabresiDimitrios KapogiannisPavan BhargavaPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2022)
Our results suggest that mitochondrial measures in circulating NEVs could serve as potential biomarkers of disease progression and provide the rationale for larger follow-up longitudinal studies.