Motor Coordination Disorders Evaluated through the Grid Test and Changes in the Nigral Nrf2 mRNA Expression in Rats with Pedunculopontine Lesion.

Lisette Blanco LezcanoEsteban Alberti AmadorMaría Elena González FraguelaGuadalupe Zaldívar Lelo de LarreaRosa Martha Pérez SerranoNadia Angélica Jiménez LunaDianet Camejo RodríguezTeresa Serrano SánchezLiliana Francis TurnerBárbara Estupiñán DíazYamilé Vega HurtadoIsabel Fernández Jiménez

Published in: Behavioral sciences (Basel, Switzerland) (2020)

Disorders of motor coordination associated with PPN injury are bilateral. The increased Nrf2 mRNA expression could represent an adaptive response to oxidative stress in the nigral tissue following pontine injury.

Keyphrases

oxidative stress
dna damage
diabetic rats
ischemia reperfusion injury
induced apoptosis
case report
heat shock