Determination of Reference Values of MDR-ABC Transporter Activities in CD3+ Lymphocytes of Healthy Volunteers Using a Flow Cytometry Based Method.

Péter SzerémyKatalin Tauberné JakabSándor BaráthAndrás ApjokKata FilkorZsolt HollóJános Márki-ZayJános KappelmayerSándor SipkaPéter KrajcsiGergely Toldi

Published in: Cytometry. Part B, Clinical cytometry (2018)

The determination of the functional activity of MDR-ABC transporters is achievable using a flow cytometry based standardized method. Having established the normal range of MAF values on CD3+ lymphocytes of a healthy population, our results allow for the development of novel flow cytometry based diagnostic tools. © 2018 International Clinical Cytometry Society.

Keyphrases

flow cytometry
multidrug resistant
peripheral blood
solid phase extraction
molecularly imprinted
nk cells
single cell
high resolution