Following cytotoxic nanoconjugates from injection to halting the cell cycle machinery and its therapeutic implications in oral cancer.
Hend M Abdel HamidZeinab E DarwishSahar M ElsheikhGhada M MouradHanaa M DoniaMarwa M AfifiPublished in: BMC cancer (2021)
Our data indicates that the cellular biological events do not predict the outcome seen in our in vivo model. Furthermore, our results suggest that AuNSs selectively enhance the therapeutic effect of small molecule inhibitors such as FGFR1i than potent anticancer drugs. Future studies are required to better understand the underlying mechanism.