Association between histamine-2 receptor antagonists and adverse outcomes in neonates: A systematic review and meta-analysis.

Victor Santana SantosMarina S FreireRuth N S SantanaPaulo R S Martins-FilhoLuis E CuevasRicardo Queiroz Gurgel

Published in: PloS one (2019)

Current evidence suggests that H2RA is associated with an increased risk of infection and NEC, but not with mortality in neonates admitted to NICU. The use of H2RA in neonates must be stringently considered when necessary.

Keyphrases

low birth weight
preterm infants
rheumatoid arthritis
disease activity
ankylosing spondylitis
cardiovascular events
risk factors
preterm birth
idiopathic pulmonary fibrosis