Evaluation of Antitumor Efficacy of Chitosan-Tamarind Gum Polysaccharide Polyelectrolyte Complex Stabilized Nanoparticles of Simvastatin.

Rishabha MalviyaShakshi RajShivkanya FuloriaVetriselvan SubramaniyanKathiresan SathasivamUsha KumariDhanalekshmi Unnikrishnan MeenakshiOmji PorwalDarnal Hari KumarAmit SinghSrikumar ChakravarthiNeeraj Kumar Fuloria

Published in: International journal of nanomedicine (2021)

The present study involves first-time synthesis of Ch-TGP polyelectrolyte complex stabilized nanoparticles of simvastatin against MCF-7 cells. It recommends that, in future, theoretical modeling and IVIVC should be carried out for perfect designing of delivery systems.

Keyphrases

induced apoptosis
drug delivery
cell cycle arrest
current status
signaling pathway
cell proliferation
hyaluronic acid