Fractures in elderly mice demonstrate delayed ossification of the soft callus: a cellular and radiographic study.

Nicholas David ClementM S GastonA H Simpson

Published in: European journal of orthopaedic surgery & traumatology : orthopedie traumatologie (2022)

Elderly mice demonstrated a delay in endochondral ossification which was associated with a decreased relative bone mineral content at the fracture site and may help assess these cellular changes in a clinical setting.

Keyphrases

high fat diet induced
middle aged
bone mineral density
wild type
metabolic syndrome
adipose tissue
postmenopausal women
bone regeneration
hip fracture
organic matter