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Relationship between body mass index and atopic dermatitis: a Mendelian randomization approach in exploring causality: a critical appraisal.

Catherina X PanY-H JeeK J MooreP KraftMaryam M Asgari
Published in: The British journal of dermatology (2021)
Atopic dermatitis (AD) is a common, chronic inflammatory skin disease with a complex etiology including genetic and environmental risk factors.1 Obesity has been associated with increased AD risk and severity,2 but a causal relationship has not been established. In the Journal of Allergy and Clinical Immunology, Budu-Aggrey et al.3 assessed the causality between elevated body mass index (BMI) and AD using a Mendelian randomization (MR)approach1 .
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