LC-MS/MS Estimation of Rociletinib Levels in Human Liver Microsomes: Application to Metabolic Stability Estimation.

Mohamed W Attwa Ali Saber AbdelhameedAdnan A Kadi

Published in: Drug design, development and therapy (2021)

RLC exhibited a moderate extraction ratio indicative of good bioavailability. The developed analytical method herein is the first LC-MS/MS assay for RLC metabolic stability.

Keyphrases

high throughput