Epilepsy, antiepileptic drugs, and the risk of major cardiovascular events.
Elinor Lee-LaneFatemeh TorabiArron LaceyBeata Fonferko-ShadrachDaniel HarrisAshley AkbariRonan A LyonsMark I ReesInder SawhneyJulian HalcoxRob PowellWilliam Owen PickrellPublished in: Epilepsia (2021)
Individuals with epilepsy prescribed antiepileptic drugs are at an increased risk of major cardiovascular events compared with population controls. Being prescribed an enzyme-inducing antiepileptic drug is not associated with a greater risk of a major cardiovascular event compared to treatment with other antiepileptic drugs. Our data emphasize the importance of cardiovascular risk management in the clinical care of people with epilepsy.