Formation and clearance of TNF-TNF inhibitor complexes during TNF inhibitor treatment.

Lea C BerkhoutM J l'AmiS KruithofE H VogelzangF HooijbergM H HartA E H BentlageD ThomasS VermeireG VidarssonA Ten BrinkeM T NurmohamedG J WolbinkT Rispens

Published in: British journal of pharmacology (2023)

Differences in TNFi structure profoundly impact the clearance of TNF, while it is unlikely that TNF itself significantly contributes to target-mediated drug disposition of TNFi.

Keyphrases

rheumatoid arthritis
emergency department