Citrobacter spp. and Enterobacter spp. as reservoirs of carbapenemase bla NDM and bla KPC resistance genes in hospital wastewater.
Josefina Duran-BedollaJuan Téllez-SosaPaola Bocanegra-IbariasAstrid SchilmannSugey Bravo-RomeroFernando Reyna-FloresTania Villa-ReyesHumberto Barrios-CamachoPublished in: Applied and environmental microbiology (2024)
family. Moreover, the identification of these resistance genes on conjugative plasmids highlights the potential for widespread transmission via horizontal gene transfer. Understanding the mechanisms of antibiotic resistance in hospital wastewater is crucial for developing targeted interventions aimed at reducing transmission, thereby safeguarding public health and preserving the efficacy of antimicrobial therapies.
Keyphrases
- klebsiella pneumoniae
- public health
- genome wide
- bioinformatics analysis
- multidrug resistant
- genome wide identification
- escherichia coli
- wastewater treatment
- healthcare
- genome wide analysis
- acute care
- staphylococcus aureus
- anaerobic digestion
- adverse drug
- dna methylation
- physical activity
- copy number
- drug resistant
- antibiotic resistance genes
- cancer therapy
- gene expression
- emergency department