Helicobacter pylori urease induces pro-inflammatory effects and differentiation of human endothelial cells: Cellular and molecular mechanism.
Mariele de Jesus SouzaJoão Alfredo de MoraesVany Nascimento Da SilvaEdward Helal-NetoAugusto Frantz UbertiAdriele Scopel-GuerraDeiber Olivera-SeveroCélia R CarliniThereza Christina Barja-FidalgoPublished in: Helicobacter (2019)
The data suggest that the pro-inflammatory properties of HPU drive endothelial cell to a ROS-dependent program of differentiation that contributes to the progression of H pylori infection.