Interplay between male gonadal function and overall male health.
Vincenzo AseroCarlo Maria ScornajenghiSalvatore IaconisGiovanni PaganoAlfonso FalconeFabrizio DinacciGiovanni PaganoDalila CarinoRoberta CorvinoAnas TreshPublished in: Journal of basic and clinical physiology and pharmacology (2024)
The process-of-male reproduction is intricate, and various medical conditions-have the potential to disrupt spermatogenesis. Moreover, infertility in males can serve as an indicator of-potential future health issue. Numerous conditions with systemic implications have been identified, encompassing genetic factors (such as Klinefelter Syndrome), obesity, psychological stress, environmental factors, and others. Consequently, infertility assessment-presents an opportunity for comprehensive health counseling, extending-beyond discussions about reproductive goals. Furthermore, male infertility has been suggested as a harbinger of future health problems, as poor semen quality and a diagnosis of-male infertility are associated with an increased risk of hypogonadism, cardiometabolic disorders, cancer, and even mortality. This review explores the existing-literature on the relationship between systemic illnesses and male fertility, impacting both clinical-outcomes and semen parameters. The majority of the literature analyzed, which compared gonadal function with genetic, chronic, infectious or tumoral diseases, confirm the association between overall male health and infertility.
Keyphrases
- healthcare
- public health
- mental health
- health information
- human health
- polycystic ovary syndrome
- systematic review
- health promotion
- metabolic syndrome
- insulin resistance
- risk assessment
- coronary artery disease
- body mass index
- current status
- squamous cell carcinoma
- genome wide
- physical activity
- skeletal muscle
- depressive symptoms
- weight loss
- papillary thyroid
- cardiovascular events
- weight gain
- risk factors
- human immunodeficiency virus
- stress induced
- lymph node metastasis
- hiv infected