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Single-cell profiling-guided combination therapy of c-Fos and histone deacetylase inhibitors in diffuse large B-cell lymphoma.

Luqiao WangZijuan WuYi XiaXueying LuJi LiLei FanChun QiaoHairong QiuDanling GuWei XuJianyong LiHui Jin
Published in: Clinical and translational medicine (2022)
Altogether, we found an HDACi, LAQ824, with high efficacy in DLBCL and provided a promising HDACi-based combination therapy strategy.
Keyphrases
  • combination therapy
  • diffuse large b cell lymphoma
  • histone deacetylase
  • single cell
  • epstein barr virus
  • rna seq
  • high throughput