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MRI-Derived AD Signature of Cortical Thinning and Plasma P-Tau217 for Predicting Alzheimer Dementia Among Community-Dwelling Older Adults.

Lei YuTianhao WangOskar HanssonShorena JanelidzeMelissa LamarKonstantinos ArfanakisDavid A BennettJulie A SchneiderPatricia A Boyle
Published in: Neurology. Clinical practice (2024)
Plasma p-tau217 outperforms an imaging-based cortical thickness signature of AD in predicting future Alzheimer dementia diagnosis. Furthermore, the AD cortical thickness signature adds little to the prediction accuracy above and beyond plasma p-tau217.
Keyphrases
  • mild cognitive impairment
  • cerebrospinal fluid
  • cognitive decline
  • cognitive impairment
  • optical coherence tomography
  • magnetic resonance imaging
  • high resolution
  • contrast enhanced
  • current status
  • computed tomography