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Severe bacterial neonatal infections in Madagascar, Senegal, and Cambodia: A multicentric community-based cohort study.

Bich-Tram HuynhElsa Kermorvant-DucheminRattanak ChheangFrederique RandrianirinaAbdoulaye SeckElisoa Hariniaina RatsimaZafitsara Zo AndrianirinaJean-Baptiste DioufArmya Youssouf AbdouSophie GoyetVéronique NgoSiyin LachLong PringTouch SokMichael PadgetFatoumata Diene SarrLaurence BorandBenoit GarinJean-Marc CollardPerlinot HerindrainyAgathe de LauzanneMuriel VrayElisabeth Delarocque-AstagneauDidier Guillemotnull null
Published in: PLoS medicine (2021)
In this study, we observed a high incidence of neonatal SBI, particularly in the first 3 days of life, in the community of 3 LMICs. The current treatment for the management of neonatal infection is hindered by antimicrobial resistance. Our findings suggest that microbiological diagnosis of SBI remains a challenge in these settings and support more research on causes of neonatal death and the implementation of early interventions (e.g., follow-up of at-risk newborns during the first days of life) to decrease the burden of neonatal SBI and associated mortality and help achieve Sustainable Development Goal 3.
Keyphrases
  • antimicrobial resistance
  • healthcare
  • risk factors
  • mental health
  • pregnant women
  • physical activity
  • type diabetes
  • preterm infants
  • smoking cessation