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Hepatitis B reactivation in occult viral carriers undergoing hematopoietic stem cell transplantation: A prospective study.

Wai Kay SetoThomas Sau-Yan ChanYu-Yan HwangDanny Ka-Ho WongJames FungKevin Sze-Hang LiuHarinder GillYuk-Fai LamEric H Y LauKa-Shing CheungAlbert K W LieChing-Lung LaiYok-Lam KwongMan-Fung Yuen
Published in: Hepatology (Baltimore, Md.) (2017)
HBsAg-negative, anti-HBc-positive patients had a high rate of HBV reactivation after allogeneic HSCT, with determinants of HBV reactivation including age ≥50 years and chronic graft-versus-host disease; treatment strategies based on these parameters may prevent HBV reactivation and subsequent complications. (ClinicalTrials.gov identifier NCT01481649.) (Hepatology 2017;65:1451-1461).
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