Identification of novel therapeutic targets for chronic kidney disease and kidney function by integrating multi-omics proteome with transcriptome.

Published in: Genome medicine (2024)

Our integrated analysis of plasma proteome and transcriptome data identifies 32 potential therapeutic targets for CKD, kidney function, and specific CKD clinical types, offering potential targets for the development of novel immunotherapies, combination therapies, or targeted interventions.

Keyphrases

chronic kidney disease
single cell
genome wide
end stage renal disease
rna seq
gene expression
dna methylation
physical activity
electronic health record
cancer therapy
human health
bioinformatics analysis
risk assessment
climate change