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Low prevalence of Plasmodium falciparum parasites lacking pfhrp2/3 genes among asymptomatic and symptomatic school-age children in Kinshasa, Democratic Republic of Congo.

Sabin S NunduHiroaki ArimaShirley V SimpsonBen-Yeddy Abel ChitamaYannick Bazitama MunyekuJean-Jacques MuyembeToshihiro MitaSteve AhukaRichard CulletonTaro Yamamoto
Published in: Malaria journal (2022)
Plasmodium falciparum histidine-rich protein 2/3 gene deletions are uncommon in the surveyed population, and do not result in diagnostic failure. The use of rigorous PCR methods to identify pfhrp2/3 gene deletions is encouraged in order to minimize the overestimation of their prevalence.
Keyphrases
  • plasmodium falciparum
  • genome wide
  • genome wide identification
  • risk factors
  • copy number
  • genome wide analysis
  • young adults
  • dna methylation
  • transcription factor