The Impact of Early Life Experiences and Gut Microbiota on Neurobehavioral Development in Preterm Infants: A Longitudinal Cohort Study.

Jie Chen Hongfei Li Tingting Zhao Kun ChenMing-Hui ChenZhe SunWanli XuKendra MaasBarry M LesterXiaomei S Cong

Published in: Microorganisms (2023)

This study explored the dynamic impact of specific OTUs on neurobehavioral development in preterm infants after controlling for early life experiences, i.e., acute and chronic pain/stress and feeding in the NICU. The gut microbiota and acute pain/stressful experiences dynamically impact the neurobehavioral development in preterm infants during their NICU hospitalization.

Keyphrases

preterm infants
early life
chronic pain
low birth weight
mental health
liver failure
respiratory failure
pain management
drug induced
spinal cord
stress induced
neuropathic pain
heat stress