The effects of metformin treatment on the ovaries and uterus of offspring.

Bulent AyasSeda KırmızıkanAdem KocamanBahattin Avcı

Published in: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology (2020)

The gestational exposure to high dose metformin may result in decreased estradiol production and subsequently decreased endometrial thickness of offspring rats.

Keyphrases

high dose
high fat diet
weight gain
pregnant women
low dose
stem cell transplantation
type diabetes
insulin resistance
metabolic syndrome
estrogen receptor
combination therapy
body mass index
replacement therapy
preterm birth