SWI/SNF component ARID1A restrains pancreatic neoplasia formation.

Sam C WangIbrahim NassourShu XiaoShuyuan ZhangXin LuoJeon LeeLin LiXuxu SunLiem H NguyenJen-Chieh ChuangLan PengScott DaigleJeanne ShenHao Zhu

Published in: Gut (2018)

Arid1a suppresses pancreatic neoplasia in a compartment-specific manner. In duct cells, this process appears to be associated with MYC-facilitated protein synthesis.

Keyphrases

high grade
induced apoptosis
cell cycle arrest
signaling pathway
transcription factor
endoplasmic reticulum stress
oxidative stress
cell death
cell proliferation
pi k akt