Dedifferentiation within well-differentiated liposarcoma of the extremity or trunk: Implications for clinical management.
William W TsengFrancesco BarrettaMarco BaiaMarta BarisellaStefano RadaelliDario CallegaroDong Hum YoonMarco FioreAlessandro GronchiPublished in: Journal of surgical oncology (2021)
In extremity or trunk liposarcoma, the presence of DD leads to significantly worse outcomes in both primary and recurrence diseases. Further study is needed to determine if these patients benefit from adjunct therapies (e.g., radiation).