Electrochemical Detection of Dopamine using a Phenyl Carboxylic Acid-Functionalized Electrode Made by Electrochemical Reduction of a Diazonium Salt.
Saima AnjumBaohua LouAmiza Tahirnull Aziz-Ur-RehmanM Rehan H Shah GilaniGuobao XuPublished in: ChemistryOpen (2022)
A glassy carbon electrode (GCE) has been modified by an in situ electrochemical reduction of an aryldiazonium salt generated from the reaction of 4-aminobenzoic acid and sodium nitrite in acidic ethanolic solution. The as-prepared phenyl carboxylic acid-modified glassy carbon electrode has been, for the first time, used for the electrochemical determination of dopamine. Under optimal experimental parameters, outstanding electrocatalytic activity, high sensitivity at a LOD of 5.6×10 -9 m, and broad linearity of 0.1 to 1000 μm were obtained. The crafted electrochemical platform demonstrated excellent stability, specificity, and anti-interference capability towards the sensing of dopamine.
Keyphrases
- molecularly imprinted
- label free
- gold nanoparticles
- ionic liquid
- solid phase extraction
- uric acid
- electron transfer
- nitric oxide
- reduced graphene oxide
- quantum dots
- metabolic syndrome
- solid state
- high throughput
- sensitive detection
- single cell
- walled carbon nanotubes
- real time pcr
- liquid chromatography
- structural basis
- tandem mass spectrometry