Porcine model of neurocysticercosis by intracarotid injection of Taenia solium oncospheres: Dose assessment, infection outcomes and serological responses.

Gianfranco ArroyoLuz M ToribioAna Vargas-CallaJuan F CalcinaEdson BernalNancy ChileMiguel ZambranoLuis A Gomez-PuertaJuan ChacaltanaMiguel MarzalJavier A BustosManuela R VerasteguiRobert H GilmanSeth E O'NealArmando E GonzalezHector H Garcianull null

Published in: PLoS neglected tropical diseases (2022)

Intracarotid injection of 5000 or more oncospheres produces high NCC rates in pigs with CNS cyst burdens like those usually found in human NCC, making this model appropriate for studies on the pathogenesis of NCC and the effects of antiparasitic treatment.

Keyphrases

endothelial cells
ultrasound guided
blood brain barrier
metabolic syndrome
combination therapy
skeletal muscle
replacement therapy
glycemic control
smoking cessation
weight loss