A Simple, Robust, and Convenient HPLC Assay for Urinary Lactulose and Mannitol in the Dual Sugar Absorption Test.
Ivana Roosevelt SequeiraMarlena Cathorina KrugerRoger D HurstRoger G LentlePublished in: Molecules (Basel, Switzerland) (2022)
The assay was easy to automate, using commonly available equipment and convenient requiring no prior laborious sample derivatization. The simplicity, reproducibility, and robustness of this assay facilitates its use in routine clinical settings for the quantification of intestinal permeability.
Keyphrases
- high throughput
- ms ms
- simultaneous determination
- high performance liquid chromatography
- tandem mass spectrometry
- liquid chromatography tandem mass spectrometry
- solid phase extraction
- endothelial cells
- gas chromatography mass spectrometry
- clinical practice
- liquid chromatography
- gas chromatography
- ultra high performance liquid chromatography