Skin commensal bacteria Staphylococcus epidermidis promote survival of melanocytes bearing UVB-induced DNA damage, while bacteria Propionibacterium acnes inhibit survival of melanocytes by increasing apoptosis.
Zhenping WangJae-Eun ChoiChia-Chi WuAnna Di NardoPublished in: Photodermatology, photoimmunology & photomedicine (2018)
Our studies show different aspects of commensal activity on melanocytes during irradiation. The possible balance achieved by the different skin commensal can influence NHM potential to become cancer cells.
Keyphrases
- dna damage
- oxidative stress
- biofilm formation
- soft tissue
- diabetic rats
- wound healing
- free survival
- staphylococcus aureus
- high glucose
- endoplasmic reticulum stress
- cell death
- dna repair
- cell cycle arrest
- pseudomonas aeruginosa
- drug induced
- escherichia coli
- cell proliferation
- case control
- radiation therapy
- risk assessment
- radiation induced