Whole gut virome analysis of 476 Japanese revealed a link between phage and autoimmune disease.

Yoshihiko TomofujiToshihiro KishikawaYuichi MaedaKotaro OgawaTakuro NiiTatsusada OkunoEri Oguro-IgashiraMakoto KinoshitaKenichi YamamotoKyuto SoneharaMayu YagitaAkiko HosokawaDaisuke MotookaYuki MatsumotoHidetoshi MatsuokaMaiko YoshimuraShiro OhshimaShota NakamuraHidenori InoharaHideki MochizukiKiyoshi TakedaAtsushi KumanogohYukinori Okada

Published in: Annals of the rheumatic diseases (2021)

Our data suggest that the gut virome can affect our body either directly or via bacteria. Our analyses have elucidated a previously missing part of the autoimmunity-associated gut microbiome and presented new candidates that contribute to the development of autoimmune diseases.

Keyphrases

pseudomonas aeruginosa
multiple sclerosis
electronic health record
single cell
big data
drug induced
celiac disease
deep learning
artificial intelligence