Chromosome 10q24.32 Variants Associate with Brain Arterial Diameters in Diverse Populations: A Genome-Wide Association Study.
Minghua LiuFarid KhasiyevSanjeev SariyaAnthony J Spagnolo-AllendeDanurys L SanchezHoward AndrewsQiong YangAlexa BeiserYe QiaoEmy A ThomasJosé Rafael RomeroTatjana RundekAdam M BrickmanJennifer J ManlyMitchell Sv ElkindSudha SeshadriChristopher Li Hsian ChenRalph L SaccoSaima HilalBruce A WassermanGiuseppe TostoMyriam FornageJosé GutierrezPublished in: medRxiv : the preprint server for health sciences (2023)
Our study reveals three novel risk loci (CNNM2, NT5C2 and AS3MT) associated with brain arterial diameters. Our finding may elucidate the mechanisms by which brain arterial diameters influence the risk of stroke and dementia.