Mechanisms Underlying Chronic Binge Alcohol Exposure-Induced Uterine Artery Dysfunction in Pregnant Rat.

Vishal D NaikKatie Davis-AndersonKaviarasan SubramanianRaine Lunde-YoungMatthew J NemecJayanth Ramadoss

Published in: Alcoholism, clinical and experimental research (2018)

This is the first study to demonstrate maternal binge alcohol consumption during pregnancy disrupts uterine artery vascular function via impairment of the eNOS vasodilatory system.

Keyphrases

alcohol consumption
oxidative stress
diabetic rats
drug induced
high glucose
pregnant women
endothelial cells
body mass index
birth weight
pregnancy outcomes
pi k akt
signaling pathway
cell proliferation