Florbetaben amyloid PET acquisition time: Influence on Centiloids and interpretation.
Emily JohnsHillary A VosslerChristina B YoungMackenzie L CarlsonJoseph R WinerKyan YounesJennifer ParkJulia Rathmann-BlochViktorija SmithTheresa M HarrisonSusan LandauVictor HendersonAnthony WagnerSharon J ShaMichael ZeinehGreg ZaharchukKathleen L PostonGuido A DavidzonElizabeth C MorminoPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)
Acquisition timing affects florbetaben positron emission tomography (PET) scan quantification, especially in amyloid-positive participants. The impact of acquisition timing on quantification varies across common reference regions. Consistent acquisitions and/or appropriate post-injection adjustments are needed to ensure comparability of PET data.