Assessment of Left Atrial Fibrosis by Cardiac Magnetic Resonance Imaging in Ischemic Stroke Patients Without Atrial Fibrillation: A Systematic Review and Meta-Analysis.
Jin Hean KohLincoln Kai En LimYing Kiat TanClaire GohYao Hao TeoJamie Sin Ying HoMayank DalakotiMark Yan-Yee ChanChing-Hui SiaLeonard Leong-Litt YeoBenjamin Yong Qiang TanPublished in: Journal of the American Heart Association (2024)
A significantly higher degree of LA fibrosis was found in patients with ESUS as compared with healthy controls. This suggests that LA fibrosis may play a significant role in the pathogenesis of ESUS. Further research is warranted to investigate LA fibrosis as a surrogate biomarker of atrial cardiomyopathy and recurrent stroke risk in patients with ESUS.
Keyphrases
- atrial fibrillation
- left atrial
- catheter ablation
- oral anticoagulants
- left ventricular
- heart failure
- left atrial appendage
- mitral valve
- end stage renal disease
- direct oral anticoagulants
- ejection fraction
- newly diagnosed
- liver fibrosis
- prognostic factors
- chronic kidney disease
- acute coronary syndrome
- venous thromboembolism