Distinct Patterns of Blood Cytokines Beyond a Cytokine Storm Predict Mortality in COVID-19.
Christian HerrSebastian MangBahareh MozafariKatharina GuentherThimoteus SpeerMartina SeibertSanjay Kumar SrikakulamChristoph BeisswengerFelix RitzmannAndreas KellerRolf MuellerSigrun SmolaDominic P EisingerMichael ZemlinGuy DanzigerThomas VolkSabrina HoerschMarcin KrawczykFrank LammertThomas AdamsGudrun WagenpfeilMichael KindermannConstantin MarcuZuhair Wolf Dietrich AtayaMarc MittagKonrad SchwarzkopfFlorian CustodisDaniel GrandtHarald SchaeferKai EltgesPhilipp M LepperRobert Balsnull nullPublished in: Journal of inflammation research (2021)
Several newly identified blood markers were significantly increased in patients with severe COVID-19 (AAT, EN-RAGE, myoglobin, SAP, TIMP-1, vWF, decorin) or in patients that died (IL-1ra, IL-8, IL-10, MCP-1, SCF, CA-9). The use of established assay technologies allows for rapid translation into clinical practice.